The article is dedicated to problem in usage of main principals of syndrome neuropsychological analysis in psychiatry. Main requirements for realization of A.R. Luria’s syndrome approach are given: accountancy of psychopathology, conceptualization of brain functioning particularities, and special attention to the researched psychological reality. The prospects for further development of neuropsychology in psychiatry, including the assessment and theoretical perspectives, are observed.

The article considers the role of different approaches to neuropsychological assessment, i.e. qualitative and quantitative analysis, from the point of view of those goals which can be put before neuropsychology in clinical practice.