Attitude to work and features of the manifestation of burnout syndrome in management activities are considered in the context of the problem of psychological provision of occupational health. The article discusses the results of an empirical study aimed at studying the characteristics of attitudes toward work in the development of the burnout syndrome in management activities, which acts as one of the key criteria for the professional health of managers. It is shown that in general, the average level of burnout syndrome is characteristic for managers, the most significant contribution to the development of which is made by such functional components as lack of help and lack of psychological support of colleagues in work, as well as problems of professional development and self-improvement. Gender differences in the development of burnout syndrome among managers are analyzed. The obtained results can be used in the development and implementation of programs for early prevention and correction of burnout of managers based on the subject-resource approach to the psychological provision of occupational health of work subjects.