In our study we compared structures of changes in quality of life in caregivers of patients with Parkinson’s disease at the early and advanced stages. The perception of patients by their relatives is revealed through a content analysis of their descriptions of patients. We found out 2 factors that influence the caregiver’s adaptation: 1) severity of patient’s motor and cognitive disturbances, and 2) caregiver’s psychological problems (bad mood, difficulties in family communication and interaction).