The article discusses the relationship of the general psychological theory of activity and work-psychology. The achievements of labor psychology as a scientific and technical discipline that combines concrete scientific concepts and theories focused on the problem of social practice. These concepts include: approaches and methods of psychological study of professional activities, research projects psychological classification of occupations; theory of work motivation; research problems of intra-individual variability of human performance under the influence of workload, theory of functional states of the subject of work, including the correction of adverse varieties; the theory of differential and developmental psychology used in professional selection and career counseling; options for teaching about the psychology of erroneous actions used in quality management and safety; complementing studies of individual forms of labor; psychosemantic professional approach to the study of consciousness and self- work experience in the psychological study of foreign object activity as the basis of analysis of the mental processes and properties of the subject of work. As a result, the analysis concluded that the general psychological theory of activity performs in relation to the role of labor psychology philosophical and methodological framework and general scientific theory in understanding the psyche of the human subject of labor. It has the status of concrete scientific theory as applied to problems of professional development and training. Psychology of work, beyond training and development, require the development of specific scientific concepts and theories that complement general psychological theory of activity.